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To determine the role of pubertal status on microvascular function in healthy children and adolescents.
The present studies sought abnormalities in microvascular function in these patients.
These findings may have implications for monitoring the effects of interventions designed to improve endothelial function and microvascular function in patients with coronary artery disease.
This study sought to examine the relationship between inflammation and coronary microvascular function in asymptomatic individuals using positron emission tomography (PET) and assessment of coronary flow reserve (CFR).
This study was conducted to investigate the effects of long-term ACE inhibitors on endothelial nitric oxide (NO) metabolism and coronary microvascular function in patients with syndrome X.
The primary aim of the present study was to determine the impact of acute changes in shear rate patterns, in particular retrograde shear rate, on microvascular function in 15 healthy, young men and women as determined via the post-occlusive near-infrared spectroscopy (NIRS) microvascular reactivity response.
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There is evidence that obesity and central fat mass impairs microvascular function that, in turn, may result in the development of hypertension [ 36, 37].
Microvascular function can, in animal models, be ameliorated by an adequate level of volume resuscitation.
Furthermore no differences concerning other metabolic parameters as cholesterol levels, body mass index, skin microvascular function and in terms of safety profile including hypoglycemia could be observed.
Thus, circulating FFAs and TNF-α are likely candidates to link adipose tissue with defects in microvascular function, at least in part by influencing insulin signaling and thereby the vascular effects of insulin.
Thus, equally interesting are the results reported by Scognamiglio et al. (25) showing that postprandial hyperglycemia induces myocardial perfusion defects in T2D patients, secondary to deterioration in microvascular function causing a decrease in myocardial blood flow.
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