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"We discovered that elderly persons with a high frequency of cognitive activity have higher microstructural integrity in brain white matter than persons with lower frequency of cognitive activity," Arfanakis said.
However, there has not yet been an evaluation of microstructural integrity in the midbrain nuclei or MFB.
The sensitivity to gray matter (GM) diffusion may be important for the examination of microstructural integrity in the brain.
In the present study, we aimed to investigate altered microstructural integrity in symptomatic acute TBI by using tract-based spatial statics (TBSS) approach.
We aimed to investigate altered microstructural integrity in symptomatic acute TBI (<1 week) by using tract-based spatial statics (TBSS) approach.
The combination of structural MRI and DTI allows parcellation of the thalami according to their cortical structural connectivity and to investigate microstructural integrity in each connectivity-defined region.
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In addition to identifying microstructural integrity abnormalities in the WM of chronic epilepsy patients, certain correlations between diffusion parameter changes and onset age or disease duration have also been found.
We hypothesized that (1) significant altered microstructural integrity occurred in the symptomatic acute TBI.
This area has previously been implicated in the control of voluntary limb movements in humans and animals (Ghez and Kubota 1977; Martin and Ghez 1988; Nioche et al. 2009; Hicks and Onodera 2012), and increased involvement of the rubrospinal system may account for the decreased microstructural integrity found in SCPs and primary motor cortex.
Interestingly, both patient groups show an increase in white matter microstructural integrity over time in these regions, which seems associated with the extent of exposure to antipsychotics.
In this study we investigated the relation between baseline microstructural integrity and change in cognitive function.
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