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Here, we describe a coupled wet-lab and computational approach that uses mathematical modeling and live-cell time-lapse microscopy to map the architecture of the HIV-1 Tat transcriptional regulatory circuit and generate predictive models of HIV-1 latency.
Here, we use atomic force microscopy to map the formation of β2-microglobulin amyloid fibrils with distinct morphologies and persistence lengths, when protein concentration, pH and ionic strength are varied.
We use non-destructive high-energy X-ray diffraction microscopy to map local crystal orientations in three dimensions in a series of tensile strain states in a zirconium polycrystal.
James et al. used a very sophisticated method employing X-ray fluorescence microscopy to map ZnO particles distribution in THP-1 cells.
10a Yet dyes that rely on absorption of light have limited sensitivity as compared to fluorescence, thus driving the development of fluorescent sensors for metals to be used in conjunction with fluorescence microscopy to map metals in cells.
Menegas et al. used a combination of a powerful anatomical technique called CLARITY (Chung et al., 2013) and light-sheet microscopy to map the input and output projections of dopamine neurons in an intact mouse brain.
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For example, for cell imaging, Avti et al. adopted photoacoustic microscopy to detect, map, and quantify the trace amount of SWNTs in different histological tissue specimens.
First, we describe the combination of two-photon excitation with fluorescence lifetime imaging microscopy (FLIM) to map the nuclear docking of the anticancer drug topotecan (TPT) at a subset of DNA sites in nuclear structures of live breast tumor cells.
We are developing an integrated system for processing images of icosahedral particles during microscopy to provide reconstructed density maps in real-time at the highest possible resolution.
As a proof of concept, scanning electrochemical microscopy was successfully used to map the topography of hydrogels with complex architecture, which are being designed as cell scaffolds.
In 2008, an in vivo two-photon microscopy study was initiated to map the cortical vascular network prior to device insertion.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com