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Wei et al. have utilized this effect using wide-field lensfree holographic on-chip microscopy to differentiate between CD4+ and CD8+ T-cells on a chip.
Using the colors on polarizing microscopy to differentiate between collagen I and III, our results showed that both collagen I (yellow and red fibers) and collagen III (green fibers) were increased in the aged kidney compared to the young adult kidneys.
This study uses oral mucosal pemphigoid specimens to investigate the utility of computer-aided fluorescence overlay antigen mapping and laser scanning confocal microscopy to differentiate subgroups of mucous membrane pemphigoid.
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SRS microscopy was able to differentiate tumor from nonneoplastic tissue in an infiltrative human glioblastoma xenograft mouse model based on their different Raman spectra.
This unprecedented resolution of genomic features would have been impossible to achieve with more conventional high-resolution microscopy, which is unable to differentiate between targets that are closer than 200 nm apart from each other, the barrier known as the "diffraction limit" set by the natural wavelength of light.
As a researcher in the Warren Warren lab, Yu spends her days as scientific sleuth, investigating how a laser-based tool called pump-probe microscopy can be used to differentiate between individual pigments of paint, even if they appear identical to the human eye.
Knowledge of the location of particles is especially important relative to the external cellular membrane; brightfield microscopy is not able to differentiate between a microparticle sitting outside the cell from one that has been internalized but still located in proximity to the membrane.
As microsporidia spores are difficult to differentiate from flour grains via microscopy, the end spore concentration in the flour environment was determined by quantitative PCR (qPCR).
hES monocytes (esMCs) were analyzed by microscopy, flow cytometry, transcriptome analysis, and tested for the ability to differentiate into macrophages.
Coherent anti-stokes Raman scattering (CARS) or stimulated Raman scattering (SRS) microscopy (see below) may be the suitable spectroscopic imaging techniques to differentiate between TAG and SE content in individual LDs in vivo.
The preliminary results show preferential staining of the abnormal tissue, as indicated by both microscopy and laser-induced fluorescence imaging, and OCT's capability to differentiate between normal mucosal areas, early dysplasia, and adenocarcinoma.
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