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Moreover, neoplastic cells of glycogen-rich carcinoma have a water-clear cytoplasm at light microscopy level, whereas sebaceous carcinoma is composed of vacuolated or foamy cells [6, 7].
We previously produced expression constructs encoding these proteins for analysis in mammalian cell cultures at both the light and the electron microscopy level.
We have combined anatomical approaches at the confocal and electron microscopy level to ex-vivo electrophysiological techniques.
We therefore examined the optic lobes of adult Drosophila flies both on EM- and light microscopy level.
In all cases, those cells identified as double-labeled at the conventional microscopy level were identified as double-labeled in the confocal microscopy analysis.
At the electron microscopy level, Hfq-MT molecules were visualized as small electron-dense particles in thin-sections of bacteria expressing the Hfq-MT fusion protein (Fig. 2).
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Morphological examination displayed no significant differences in heart tissues of WT and Kir6.2−/− mice under both light and electron microscopy levels.
Correlative microscopy, on both light and electron microscopy levels, was used as a convenient experimental methodology, providing evidence of intracellular localization of nanoparticles and their displacements from the application points.
At tissue level, the structural organization of the stem samples of treated and non-treated plants was similar, with no signs of damage at light and electron microscopy levels.
Using an in situ localization approach at both light and electron microscopy levels, it has been reported that in walls of proliferating cells, the levels of esterified pectins were higher than in the differentiating cells, which showed cell walls rich in non-esterified pectins [ 17, 18].
Where scores were ambiguous, decisions were based on morphology at the light-microscopy level.
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