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Recent advancements of super-resolved fluorescence microscopy have revolutionized microscopic studies of cells, including the exceedingly complex structural organization of cell nuclei in space and time.
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Two-photon microscopy has revolutionized life sciences by enabling long-term imaging of living preparations in highly scattering tissue while minimizing photodamage.
Fluorescence light microscopy has revolutionized live imaging of developing embryos (Khairy and Keller, 2011; Mavrakis et al., 2010; Megason and Fraser, 2007).
Scanning tunneling microscopy (STM) [1] and atomic force microscopy (AFM) [2] have revolutionized surface sciences by enabling the study of surface topography and other surface properties at the angstrom-to-micrometer scale.
Single molecule based super resolution (SM-SR) techniques have revolutionized fluorescence microscopy, achieving spatial resolution of approximately 20 nm, an order of magnitude improvement from conventional fluorescence microscopy that is limited by diffraction to λ/2NA or approximately 250 nm [ 1– 5].
The improved sensitivity, resolution, and versatility of fluorescent microscopy and the discovery of fluorescent proteins have revolutionized imaging in basic science and biomedical applications [ 102, 103].
X-ray and cryo-electron microscopy studies of the ribosome and its subunits have revolutionized the field of ribosome research.
Recent developments in detector hardware and image-processing software have revolutionized single particle cryo-electron microscopy (cryoEM) and led to a wave of near-atomic resolution (typically ∼3.3 Å) reconstructions.
The HST's discoveries have revolutionized astronomy.
(The idea is said to have "revolutionized" the industry).
Few would argue they have revolutionized investing.
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