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Recent developments in cryo-electron microscopy enabled the structural characterization of complete yeast and mammalian mitoribosomes at near-atomic resolution.
Recent developments in ultrasensitive fluorescence microscopy enabled the detection and detailed characterization of individual biomolecules in their native environment.
Live cell confocal microscopy enabled the detection of colocalized RHO-CT20p (red fluorescence) with organelles (green fluorescence).
In the early 1990s, advances in light microscopy enabled the discovery of intraflagellar transport (Kozminski et al. 1993).
The analysis of the extracts by DAPI-staining microscopy enabled the correct evaluation of the amount and quality of the nuclei preparations.
High-content single cell microscopy enabled the time-resolved quantification of both the population of monocytic precursors and the emerging osteoclasts.
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Enabled by novel molecular markers, fluorescence microscopy enables the monitoring of multiple cellular functions using live cell assays.
The phase images of force microscopy enable the separation of the graphene domains from the naked areas of Cu foil.
In situ transmission electron microscopy enables the imaging of biological cells, macromolecular protein complexes, nanoparticles, and other systems in a near-native environment.
It shows that polarization-resolved SHG microscopy enables the determination of the collagen fibril orientations within the corneal lamellae using epi-detected signals although raw B-SHG images are spatially homogenous.
Two such alternatives exist: First, the technique of corneal confocal microscopy enables the direct visualization of small corneal nerve fibers in vivo, has been shown to detect small-fiber damage earlier than IENFD in skin biopsies on the dorsum of the foot (23), and detects nerve repair within 6 months of pancreas transplantation (24).
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