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Despite endothelial deletion of CD146, CD146EC-KO mice did not exhibit overt defects or detectable abnormalities in organ morphology upon analysis by light microscopy (data not shown).
A thickness of 3,530 nm and pore sizes ranging from 25 to 45 nm in diameter were determined using scanning electron microscopy (data not shown).
No differences were seen after staining or by microscopy (data not shown).
The differential bacterial accumulation was confirmed by fluorescence microscopy (Data not shown).
Each of the 18 newly isolated mycobacteriophages was examined by electron microscopy (data not shown).
On two samples of normal and scleroderma skin, we performed electron microscopy (data not shown).
In the presence of toxin, CHO PR328 cells exhibited reduced growth as confirmed by phase-contrast microscopy (data not shown).
In addition, the myofilaments in these transgenic animals appear disorganized when viewed with polarized light microscopy (data not shown).
This was determined both by laser scanning cytometry (LSC; figure 1A) and by immunoflourescent microscopy (data not shown).
Although no gross morphological differences were observed by scanning electron microscopy (data not shown), ultrastructural analysis by transmission electron microscopy (TEM) showed significant changes.
We observed massive formation of G418-resistant colonies, most of which showed detectable GFP expression by fluorescent microscopy (data not shown).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com