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Given the significant functions of collagen in articular cartilage, SHG microscopy could have profound implications for cartilage studies.
Blood, stool and urine microscopy could have yielded valuable additional information, but were not part of the study protocol for logistical reasons [ 2].
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Improper use of antimalaria drugs based on clinical diagnosis alone or on misdiagnosis as a result of poor microscopy technique or interpretation could have accelerated the onset of resistance.
Our measurement of malaria was limited to microscopy examination of placental smears and could have been inexact; those with no evidence of malaria may have had very low-density infection and may have been misclassified as having no malaria.
However, confocal microscopy showed the presence of filaments that could have been fungal mycelium.
Thus, although at first glance, the LAM sensitivity of 31% may seem modest the high specificity confers rule-in value enabling a rapid diagnosis in approximately a third more of patients than could have been obtained with microscopy.
Nevertheless, because of the small tissue area examined by electron microscopy, we cannot exclude that a similar patchy lesion could have been overlooked in some other subjects.
A limitation of our study could have been the use of light microscopy to identify immune and inflammatory responses in lung sections.
This is further supported by microscopy investigations which even suggest that a biaxially alignment could have taken place during crystal growth.
This implies that when using a fast camera, SOFI could have a significant speed advantage over localization microscopy.
The performance of the TB control programme could have been influenced by low coverage or supply of microscopy and basic facilities.
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CEO of Professional Science Editing for Scientists @ prosciediting.com