This would enable high-throughput tracing of neurons using information-rich barcodes (see the work of the Zador lab at CSHL and our IARPA MICRONS project) in combination with high spatial resolution (via improved forms of expansion microscopy combined with fluorescent in-situ sequencing) and molecular annotations such as in-situ transcriptomics and highly multiplexed proteomics.
Scanning electron microscopy combined with focused ion beam allowed observing sections containing secondary cracks.
Laser scanning confocal microscopy combined with fluorescence recovery after photobleaching is used to quantify the diffusion of the drug conjugate.
The capsid structure of PcV was recently determined using cryotransmission electron microscopy combined with three-dimensional image reconstruction.
Microscopy, combined with RNA-dectection techniques, can be used identify the RNA transcripts produced from each barcode in each cell — in this way, the barcodes attached to deleted scratchpads can be identified.
To address this question the native spliceosomes were analyzed and reconstructed in the context of the intact particle, using electron microscopy combined with image processing.
This work was designed to specify root ageing on an ultrastructural scale by transmission electron microscopy combined with microanalysis by electron energy loss spectroscopy.
Here, we used electron microscopy combined with genetic labeling to define the three-dimensional arrangement of the S. pombe Ccq1 Tpz1 Poz1 (CTP) complex.
The obtained material was characterized by X-ray diffraction (XRD), scanning electron microscopy combined with energy-dispersive spectrometry (SEM/EDS) and heat flow calorimetry techniques.
We used scanning electron microscopy combined with focused ion beam (FIB-SEM) to visualize the nano-scale pore structure of the paper coating layer.
The concentration of the two key elements — Al and Ti — was studied using scanning electron microscopy, combined with energy-dispersive X-ray spectroscopy.
