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To understand the mechanism of action, we performed fluorescence microscopy and observed ultrathin slices of nanoparticles-treated bacterial cells under transmission electron microscope (TEM).
The cell morphology for OP1 was analysed by compound microscopy and observed to display morphological characteristics consistent with the Gram-positive reaction; the colonies were rod-shaped, circular with a crenate margin.
Ghadially et al. (Ghadially et al., 1983) examined human menisci with electron microscopy and observed disruption or fragmentation and parting of collagen fibrils in the injured portions of torn menisci.
When the hybrid gold/polymer/nucleic acid nanoparticles are added to human primary brain cancer cells in vitro, they are internalizable by cells and reach the cytoplasm and nucleus as visualized by transmission electron microscopy and observed through exogenous gene expression.
To examine whether amphioxus has lymphocyte-like cells, we dissected the gills of amphioxus under light microscopy and observed that a cluster of cells contained large, darkly stained nuclei and a thin rim of cytoplasm, which were highly reminiscent of mammalian lymphocytes (Figure 1).
To demonstrate the high degree of co-expression of the VDR and Runx2 proteins, we examined double stainings by confocal microscopy and observed that chick preosteoblasts are significantly enriched in both proteins (Fig. 1 e-h).
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Effects on cell growth, survival or morphology were initially analysed by light microscopy (Nikon Eclipse TS100 microscope) and observed changes documented by digital imaging.
To verify whether bacteria retained their flagellae, we performed transmission electron microscopy (TEM) and observed that the wild-type PAK and mutant bacteria (L94A and Q83A) possessed flagella (Fig. 1).
In order to further examine the pathological abnormalities of Bst+/– mice, the authors performed electron microscopy in RGCs and observed abnormal mitochondria morphology with irregular borders and lacking cristae.
To study how these pomegranate-like structures (PLSs) relate to cells, we carried out a scanning electron microscopy (SEM) study and observed membrane-bound structures with similar shape, size, and position relative to the cell as the PLSs we identified by TEM.
Tuberculosis services are decentralized, with quality-assured smear microscopy and directly observed treatment through all public health facilities and through a network of community DOT providers.
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