Exact(4)
Microscopic tissue sections of interest were taken on PALM slides and stained with Toluidine Blue for laser microdissection with PALM microbeam systems.
Microscopic tissue sections were stained by hematoxylin and eosin (H&E) and examined to ensure purity of tumor-containing and non-tumor containing regions.
Membrane androgen receptors are membrane proteins [ 5, 12], expected to be (partially) denatured in microscopic tissue sections by formalin fixation, paraffin embedding and high temperatures, conditions known to modify integral membrane proteins.
Another potential source of non-specific staining could be the association of the ligand (testosterone) with iARs, due to the fact that microscopic tissue sections contain broken (sectioned) cells.
Similar(56)
Metastatic colonization was evaluated by gross examination and microscopic inspection of tissue sections.
Figure 3 shows representative microscopic images of tissue sections from different groups stained with H&E.
Microscopic examination of tissue sections stained with hematoxylin and eosin revealed no evidence of bacterial infection and no W. bancrofti adult worms or microfilariae.
This technique allows for the accurate procurement of cells from specific microscopic regions of tissue sections, and therefore enables the molecular genetic analysis of pure populations of malignant breast cells in their native tissue environment [ 18].
Curnis et al (2002) investigated the therapeutic potential of recombinant human TNF fused to an NGR peptide that mediates a preferential localisation of the protein at sites of tumour neo-vasculature, as assessed by microscopic analysis of tissue sections.
Gross examination of vital organs such as brain, kidney, spleen, and liver of rats and microscopic examination of tissue sections prepared from these organs did not observe any histopathological alteration in any treated rats during subchronic toxicity studies.
Microscopic analyses of histologic tissue sections revealed that there were no observable abnormalities in various tissues, including the brain (Figure 1E, not shown).
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