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The fluorescence microscopic studies in this work further revealed the localization of LDH within the mitochondria.
Interestingly, our confocal fluorescence microscopic studies in PC-3 cells showed the co-localisation of LMP2 and DAPI staining, indicating the presence of LMP2 in the nucleus of PC-3 cells.
This distinguishing feature of CoTC-mediated termination is supported by electron microscopic studies in Drosophila that show that release of pre-mRNA from transcription sites prior to 3′ end processing is a common occurrence (Osheim et al., 2002).
Microscopic studies in tumor slides confirmed that the anti-tumor effect of OGX-427 was associated with a decrease in Hsp27, eIF4E and ki67 proliferation index and an increase in caspase-3-dependent apoptosis.
In mammalian hepatocytes, the degradation of peroxisomes by autophagy was noted quite early by electron microscopic studies in rodents treated with hypolipidemic drugs (Leighton et al. 1975; Moody and Reddy 1976; Staubli et al. 1977) (Fig. 2e).
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Convinced of the value of the microscope as a tool in all sciences, Sorby began to prepare thin sections of rocks (about 0.025 millimetre, or 1/1000 inch thick) for microscopic study in 1849.
To investigate whether isolated islets express iNOS protein we performed a confocal microscopic study in GK islets.
Rapid diagnoses or determinations of adequacy could be given on core biopsy specimens, margins could be assessed by either ex vivo tissue imaging or intraoperative consultations at the time of primary surgical excision and CSLM could aid in the selection of sections to submit for microscopic study in large primary excisions or in the evaluation of re-excision specimens.
Schizosaccharomyces pombe has emerged as a model organism for study of these processes because its simpler genome encodes a smaller and less redundant proteome than in mammals, the facility of genetic manipulation, and the amenability of the cytoskeleton to microscopic study in living cells.
Light-microscopic studies in reduced systems indicate that distribution of essential docking factors is complex, with accumulations of individual factors in partially overlapping microdomains (Lang et al. 2001; Lang and Jahn 2008).
Electron-microscopic studies in primates show a diameter of around 0.4 μm for the papillomacular bundle with a complete lack of the larger 2.5 μm fibers seen elsewhere in the retina.
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