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Importantly, optical manipulation of biological samples is fully sterile, compatible with microscopic imaging and can be easily automated for high throughput image-based processing.
This paper first reviews the fundamental concepts of microscopic imaging and introduces the technical features and associated clinical applications of optical microscopes, electron microscopes, scanning tunnel microscopes, and fluorescence microscopes.
Microscopic imaging and dynamic mechanical analysis revealed a double-network structure of the composite matrices.
This cosmos is only now revealing itself as a result of scientific discoveries based on better microscopic imaging and DNA analysis.
We describe automation in time-lapsed microscopic imaging and how this technology is providing new insights into stem cell biology.
Microscopic imaging and analysis were applied to observed and reveal the effect of self-regenerated units on the wear behavior.
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It bridges the gap between common macroscopic and microscopic imaging modalities and opens up new three-dimensional (3D) insights in tumor biology.
By contrast, image cytometry techniques consist of microscopic imaging techniques and computer aided image analysis that can preferentially analyze adherent cells.
The chapter explains many types of microscopic imaging techniques and each of them provides a different information representation or produces unique information.
Advances in microscopic imaging technologies and associated computational methods now allow descriptions of cellular anatomy to go beyond 2-dimensions, revealing new micro-domain dynamics at unprecedented resolutions.
Two-photon fluorescence microscopic imaging (2PFM) and two-photon fluorescence lifetime imaging (2P-FLIM) were performed on a modified Olympus Fluoview FV300 microscope system coupled with the tunable Coherent Mira 900F Ti:sapphire laser and a compact FLIM system from PicoQuant, Germany.
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