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Incidental microscopic findings, including acinar cell focal hyperplasia or necrosis, duct intraluminal concretion and subacute or acute inflammation were observed in the pancreas across all groups including controls and were not considered toxicologically significant based on incidence, severity, distribution and historical control data (Table 2).
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Diffuse and focal XPN microscopic findings include a mixed acute and chronic inflammatory cell infiltrate with giant cells and lipid-laden macrophages (foam cells) (Fig. 21).
Microscopic findings include a growing mass of atypical cells containing clear, partially oxyphillic cells, in solid and alveolar structures with broad fibrosis.
Significant microscopic findings included those in the lungs and kidneys.
Electron microscopic findings included disruption of the mitochondrial architecture (i.e., mitochondrial swelling and clearing of matrix densities), myofibrillar loss, disorganization of the normal alignment of sarcomeres, and occasional myocytes showing nuclear hypertrophy or peripheral clumping of the nuclear chromatin.
Microscopic findings included a granulomatous reaction indicated by lymphohistiocytic elements with large numbers of multinucleated Langhan-type giant cells and numerous isolated yeast-like organisms with a birefringent membrane isolated or in chains alternating with some piriform elements showing simple gemation.
The objective of this report was to describe the clinical and post-mortem findings including the macroscopic and microscopic anatomy of selected organs in a cow with polysplenia and situs ambiguus.
We did not consider the ascites caused by the alginate to be inflammatory based on the size of the alginate molecules and the microscopic findings of inflammation, including inflammatory cell infiltration.
Pathological findings included thyroid capsular invasion in 47%, vascular invasion in 15%, microscopic positive margins in 28%, soft tissue invasion in 30%, and bilateral thyroid involvement in 36%.
Key findings include: 1.
Other findings include.
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