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With the help of laser scanning confocal microscope, we demonstrated that these probes could simultaneously sense Cys and GSH in Hela cells using multicolor imaging.
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Using in situ, quantitative nanomechanical tests inside a transmission electron microscope, we demonstrate that certain nanoscale metallic glass samples are exceptions to this general rule.
Here, using a scanning tunneling microscope tip, we demonstrate engineering of the energy levels of the YSR states by placing interstitial Fe atoms in close proximity to adsorbed Fe atoms on an oxidized Ta surface.
By employing a full-field Bragg X-ray diffraction microscope (XDM), we demonstrate that a real space image with a field of view of ~15 × 15 μm2 and ~70 nm lateral spatial resolution is captured with an acquisition time as small as 50 ms.
In conclusion, we demonstrated a DH-PSF microscope with efficient photon collection and its application in 3D PALM.
In terms of spatial resolution, we demonstrate with scanning electron microscope and white light interferometry that a full ablation removes between 0.4 and 0.7 μm of material, depending on ablation parameters.
Here, we demonstrate using atomic-force-microscope nanoindentation that the modulus of nanostructured PDMS is doubled, while that of nanostructured ORMOCER increases by an order of magnitude, when compared to their flat counterparts.
Despite this ambiguity, which is most likely caused by the resolution limit of the microscope, we were able to demonstrate the colocalization of the ubiquitin signal with the late endosomal/lysosomal cellular compartment in pSap deficient neurons.
In order to explore the feasibility of employing 2P endoscopy for ex vivo study of the aqueous outflow pathway using an anterior segment perfusion culture system of the eye, we constructed a light-weight, catheter-like microscope and demonstrated its capability for imaging human TM.
Toward this end we have built a mobile phone-mounted light microscope and demonstrated its potential for clinical use by imaging P. falciparum-infected and sickle red blood cells in brightfield and M. tuberculosis-infected sputum samples in fluorescence with LED excitation.
After treatment of MCF7 cells with compounds 4, 5, and 8, fluorescence microscope examination demonstrated the presence of nucleus shrinkage or segmentation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com