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Exact(5)
The mean population mutation rates of microsatellites do not significantly differ in motifs of di-, tri-, and tetra-nucleotide repeats for the studied rice species.
This is not surprising, as these microsatellites do not cause a shift in the reading frame in case of a slippage event [ 25].
The abundance of microsatellites within the coding region was three-fold lower than intergenic regions and, when present, microsatellites do not show useful allelic variability.
Interestingly, microsatellites do not only tend to cluster but the adjacent repeat types of compound microsatellites have very similar motifs: in most cases (>90%) these motifs differ only by a single mutation (base substitution or indel).
In all eight species about 33% of the tri-SSR compound microsatellites exhibit this pattern [see Additional file 2: Table S11], which suggests that most (67%) tri-SSR compound microsatellites do not originate by a nesting of microsatellites.
Similar(55)
Mutations in these microsatellites did not correlate significantly with clinical attributes of the tumors in our analysis.
Regions containing microsatellites did not show any additional ETS consensus over-representation after repeat filtration (Table S2).
Fourteen microsatellites did not amplify in E. urophylla (Table 2).
The remaining 32 sequences containing microsatellites did not allow optimal primer design.
However, whether we used different weights or not for indels versus microsatellites did not affect the topology.
However, a direct comparison of CDK1SA between patients with stable or unstable microsatellites did not attain significance (Supplementary Figure 4).
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