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Approximately 6,000 years ago, humans began to tap the biological processes of microorganisms in order to make bread, alcoholic beverages, and cheese and to preserve dairy products.
In this article we define bioterrorism as the deliberate use of naturally occurring or bioengineered microorganisms in order to cause harm to people, animals, or plants.
As a PhD student in Harris Wang's lab, I am working on developing technologies for engineering diverse species and communities of microorganisms in order to study their evolution and to endow them with new capabilities.
In natural environments, the first step of microbial embedding in a mineral casing, lasting from hours to months, needs to be followed by cementing of the whole system, including both sediments and mineralized microorganisms, in order to preserve traces of life over geological time lasting from millions to billions of years.
The strain may also be useful as a genetic resource for engineering pentoses metabolism in oleaginous microorganisms in order to improve their ability to convert sugar mixtures to lipid.
Many plants allow intracellular accommodation of symbiotic microorganisms in order to improve nutrient uptake.
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The overview of the subject reveals the requirement for in-depth information on the overall regulation of P. pastoris metabolism that can enable fine-tuning bioreactor operation parameters in relation with the physiology of the microorganism in order to develop new strategies for the enhanced r-protein production.
In ICU patients, empirical use should be avoided, and definitive therapy should be reserved to patients in clinical stable condition, after microbial documentation and results of susceptibility tests, together with adapting the administered dose and modalities of infusion to the MIC of the infecting microorganism in order to reach pharmacological targets.
The microorganisms found, in order of frequency were: Acinetobacter baumannii (27.9 %), enterobacteriaceae (16.1 %), Klebsiella pneumoniae (13.3 %), Candida albicans (8.9 %), Pseudomonas aeruginosa (5.4 %) and Staphylococcus aureus (3.8 %).
Surveillance cultures of the throat and rectum were obtained on admission and thereafter at days 4, 8 and 12 to look for potentially pathogenic microorganisms (PPMs) in order to distinguish the community acquired from those acquired during the ICU stay.
The increasing occurrence of MRSA in hospitals makes the typing of these microorganisms important in order to determine whether the strains involved in nosocomial infections or in possible foci of transmission are related to a specific clone, i.e., whether they have a common origin [ 13].
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