Average area-level (residential) exposure was modeled for each pregnancy together with trimester-specific exposure estimates (micrograms per liter) based on mother's residence at birth and her exact pregnancy period.
We converted measured metal concentrations (parts per million) in the individual lip product samples to metal intakes (micrograms per day) based on usage patterns reported by Loretz et al. (2005), assuming average and high use (resulting in oral intake of 24 and 87 mg of product per day, respectively) (Table 3).
Measured metal concentrations (parts per million, weight/weight) were converted to estimated daily metal intakes (micrograms per day) based on lip product use data from a study of cosmetic product use among 360 women (ages 19 65 years) from ten different U.S. geographical regions (Loretz et al. 2005).
Under the air district's rules, Exide's lead emissions cannot cause the outdoor air concentration of lead to exceed 0.15 micrograms per cubic meter based on a 30-day average.
Under air district rules, Exide's lead emissions cannot cause the outdoor air concentration of lead to exceed 0.15 micrograms per cubic meter based on a 30-day average.
Urinary DON concentrations (nanograms DON per milliliter of urine) were converted to urinary DON amounts (micrograms DON per day) based on 24-hr urine volume.
The injected dosages of 10 micrograms of NE were based on what was previously reported in the neuropathic pain literature and also on a pre-trial NE injections in ourselves that demonstrated no untoward effects and no pain elicitation with this dosage.
Residential THM exposure (micrograms per liter) was based on the time-weighted annual average municipal THM level at all residences since the age of 15 years (years prior to age 15 were excluded to minimize missing or poorly recalled residential data in those early years).
The amount of 84 micrograms of plasmid/implant is based on the manufacturing procedure of the plasmid/COPROG-mixture and represents the highest possible "load" of COPROG to the fibrin component without compromising the maximum clotting firmness (MCF) of the fibrin glue.
The average dose of a drug use period is modelled as the average DDD per day, as the purchased amount is recorded as DDDs in the prescription register, and is independent of changes in units (grams, milligrams, micrograms etc).. PRE2DUP is based on modelling of personal drug purchasing behavior.
