Sentence examples for microenvironment necessary for from inspiring English sources
This site was defined as specialized microenvironment necessary for maintenance of stem cells.
Macrophages comprise an essential component of the mammary microenvironment necessary for normal gland development.
This process guarantees the homeostasis of the brain microenvironment, necessary for neuronal activity and proper functioning of the CNS.
These results offer an opportunity to reconstruct the extrinsic microenvironment necessary for efficient differentiation of DPSCs, and eventually facilitate their application in tissue regeneration.
CCR2 may be critical for recruiting essential bone marrow-derived cells important in creating a microenvironment necessary for normal MPC function and muscle regeneration.
A role of androgens along the epididymis in creating the microenvironment necessary for maturation and storage of spermatozoa has thoroughly been analyzed by Hinton and Palladino [ 42].
Productive viral infection requires changes to the cellular metabolic landscape in order to obtain the building blocks and create the microenvironments necessary for the viral life cycle.
Therefore, the development of a high-throughput screening assay that could mimic the cancer microenvironment was necessary for identification of natural products that has the potential to modulate NK cell activity.
Tumours are complex organs composed of tumour cells, stromal fibroblasts, endothelial cells and cells of the immune system; and reciprocal interactions between these cell types in the tumour microenvironment are necessary for tumour growth [ 21, 22].
In the context of breast cancer, recent studies have shown that the cross-talk and interaction of the tumor cells with their surrounding microenvironment is necessary for tumor progression (Tlsty and Coussens, 2006; Polyak et al., 2009; Dvorak et al., 2011; Boudreau et al., 2012; Conklin and Keely, 2012; Fordyce et al., 2012).
Another possibility is that the glandular microenvironment comprises factors necessary for prolonged plasma cell survival and that autoantibodies are being produced by plasma cells independently of activation and differentiation of new B-cells.
