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The tumor microenvironment is composed of neoplastic and stromal cells and a great number of immune cells.
The tumour cell microenvironment is composed of endothelial cells, microglia and leukocytes.
Tumor microenvironment is composed of tumor cells, fibroblasts, endothelial cells, and infiltrating immune cells.
Tumor microenvironment is composed of many different types of non-malignant cells including mesenchymal stromal cells (MSC) [ 7].
The bone marrow microenvironment is composed of many cellular and cellular components such as endothelial cells, stromal cells, osteoclasts, osteoblast, immune cells, fat cells, and extracellular matrices.
The breast microenvironment is composed of extracellular matrix (ECM) and numerous stromal cell types, including endothelial and immune cells, fibroblasts, and adipocytes.
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Tumor microenvironments were composed with heterogeneous cells and molecules [ 42]. pVHL enhanced extracellular matrix protein, thus prolonged the tissue morphology and inhibited tumor metastasis HIFs independently [ 17].
Tumor grows in a complicated microenvironment, which is composed of stromal fibroblasts, endothelial cells, and infiltrating immune cells.
The mechanical interaction of contractile cells with their microenvironment, which is composed of polymeric extracellular matrix (ECM) proteins and other cells, can be modeled most simply as a cell pulling on a spring (FIG. 1A).
The gradual formation of liver cancer is accompanied by the development of a specific tumour microenvironment, which is composed of immune cells, small vessels, myofibroblastic cells, and extracellular matrix components (Faouzi et al, 1999; Bhowmick et al, 2004; Albini and Sporn, 2007).
The discrete value model in Figure 1 describes the interactions of different signaling components in the tumor microenvironment, which is composed of m = 96 nodes, including 3 control nodes (input signals: Hh, AGE, Wnt), and 9 output nodes (Angiogenesis, Proliferation, Apoptosis in 3 different cells).
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