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In addition, vasoconstrictors, such as norepinephrine, may have paradoxical effects, and their impact on cerebral microcirculation has not been determined yet.
To our knowledge, the simultaneous assessment of LV pressure/volume parameters, along with sublingual microcirculation has not been performed before in these experimental conditions.
Yet, the relevance of these slopes in determining microcirculation has not yet been fully determined.
However, the effect of pulmonary exposure to PM on endothelial cell function in the systemic microcirculation has not been evaluated.
The microcirculation has not been evaluated in septic patients; in contrast, several studies have examined macrocirculatory changes with inconsistent results [ 3].
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Nevertheless, our findings emphasize that in this group of postoperative patients, the villi microcirculation had not only a different physiologic behavior but also a higher prognostic implication.
However, the effects of a high-dosed supplementation of L-arginine on the microcirculation have not been well characterised.
However, adverse effects of cc5128sedation have not been fully evaluated; in particular, effects of benzodiazepine and opiates on microcirculation have not been extensively studied.
Although StO2 derived variables have demonstrated their ability to detect the effects of DrotAA on microcirculation, it has not been proven that these changes have repercussion on outcome.
Cold exposure can be adapted for exercise or therapeutic purposes, but its impact on microcirculation in healthy humans has not been well defined.
Computer software has recently been developed to automate the analysis of microcirculation film images, but as yet has not been validated for this purpose (Dobbe et al. 2008).
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