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Antibiotic therapy was changed correctly after microbiology data in 21 of 88 patients (24%).
Efforts should be focused on implementing bundles of measures based on best evidence for diagnosis and treatment, integrating clinical features and microbiology data, in order to obtain a simple and effective approach to management of pneumonia.
Of the remaining patients, antibiotics were streamlined in 56 (23%) patients and remained unchanged in 14 (6%) patients based on microbiology data, in 38 (16%) patients despite microbiology data favouring de-escalation, and in 113 (46%) patients due to unknown aetiology.
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This platform will help us survey abnormal events by using all of the clinical microbiology data available in the laboratory.
Analysis of microbiology data generated in support of patient care by clinical laboratories across the United States has been used in the past to provide perspective on a variety of antimicrobial resistance trends among key bacterial pathogens [ 3- 6].
Of these, 15 hospitals in 1999, 23 hospitals in 2000 and 2001, and 24 hospitals in 2002 and 2003 provided adequate drug-use and microbiology data for inclusion in this study.
Microbiology data are given in table 2. VAP was caused by Gram-negative pathogens in 13 patients and by Gram-positive pathogens in 9 patients.
Clinical and microbiology data were recorded in a preestablished protocol and entered into a database.
PR participated in microbiology data acquisition, analysis and revision of the manuscript.
In the present investigation, retrospective analyses of microbiology data using a statistical technique were promising in terms of identifying plausible C. difficile clusters.
For C. difficile, research has been conducted to assess the effectiveness of different statistical methods, including the Knox test [ 20, 21] and computer-assisted algorithms using microbiology data [ 22] to enhance surveillance in healthcare facilities.
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