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The benefits of routine microbiological screening of neonatal body surface to predict and prevent sepsis are controversial.
In 2012 and 2013, the German Commission for Hospital Hygiene and Infectious Disease Prevention recommended a microbiological screening of infants on neonatal intensive care units.
Undiagnosed TB remains highly prevalent in this population as identified in studies of intensified TB screening pre-ART [ 2– 4]; the highest TB diagnostic yield achieved by microbiological screening of all HIV-infected individuals regardless of presenting symptoms [ 5].
Microbiological screening of essential oil from many plants (Pimpinella anisum L. (anised), Syzygium aromaticum L. (clove), Cuminum cyminum L. (cumin), Allium sativum L. (garlic), Laurus nobilis L. (laurel), Citrus sinensis (L).
On 25 October 2011, a microbiological screening of all infants in the NICU was introduced and then extended to a twice weekly screening of all patients in the paediatric clinic and an admission screening.
Before screening was introduced, cases were identified only if they had developed signs of infection or if mechanical ventilation had prompted a microbiological screening (it was current practice on the ward to perform microbiological screening of sputum in mechanically ventilated infants).
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This study highlights the importance of microbiological screening for multidrug-resistant strains in ICUs, particularly among patients from regions in which multidrug-resistant bacteria are known to exist.
Microbiological screening for the presence of Candida was prospectively carried out on admission and twice weekly thereafter according to a standardised protocol that was part of a SDD/Selective Oropharyngeal Decontamination (SOD) trial [ 12].
Other strategies to minimize risk include the use of alternative prophylactic agents (e.g. nitrofurantoin and/or fosfomycin), [ 40, 41] the use of targeted prophylaxis based on microbiological screening for resistance, or alternative surgical approaches, such as transperineal biopsy.
Epidemiological and phylogenetic analyses consistently indicated that there were additional, undiscovered cases prior to the onset of microbiological screening and that the spread of the pathogen remained undetected over several years, driven predominantly by person-to-person transmission.
In practice, it is primarily performed using microbiological screening methods, because of their high cost-effectiveness compared to physical chemical detection.
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