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The main efficacy variables were clinical and microbiological outcome at day 7. Analyses on both valid patients and intention-to-treat populations were performed.
Moreover, the degree to which the inherent complexity of CF respiratory infections complicates the process of determining treatment impact and the need to identify more robust microbiological outcome measures will also be reviewed.
Objectives: We assessed the impact of amikacin pharmacokinetic and pharmacodynamic parameters on clinical and microbiological outcome in these patients.
Comparing the microbiological outcome of inhaled ceftazidime amikacin versus inhaled colistin as adjunctives to conventional iv antibiotics in treating gram negative VAP.
Descriptive data and data regarding the microbiological outcome variables were analyzed using IBM SPSS Statistics 22 Version 22.0 (IBM Corp. Armonk, NY: IBM Corp .. Multilevel models were analyzed using MLwiN version 2.12 (Centre for Multilevel Modeling, University of Bristol, Bristol, UK).
The sample from day 14 is the microbiological outcome measure.
Similar(41)
Microbiological outcomes were similar to clinical outcome, with 83.6% microbiologic success rate among ESBL producers.
To compare the microbiological outcomes of membrane filter system and blood culture bottle techniques in culturing diluted vitrectomy cassette vitreous.
This study was designed to compare cefepime exposures with microbiological outcomes in ESBL and non-ESBL infections and determine the pharmacodynamic profiles associated with successful outcome.
We sought to evaluate published evidence regarding clinical or microbiological outcomes related to the use of inhaled antibiotics other than aminoglycosides, polymyxins and aztreonam.
To describe outcomes associated with nosocomial bacteremic Staphylococcus aureus pneumonia (NBSAP) and to determine whether delay in adequate antimicrobial treatment is a risk factor for negative clinical and microbiological outcomes.
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