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When further analysing the present results, it was also noted that nonsurgical treatment of peri-implantitis commonly failed to result in major microbiological improvements [32, 34 37], thus potentially explaining the frequency of residual BOP scores at respective sites.
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This is likely a function of selecting children whose symptoms were due to fastidious organisms and non-bacterial causes as well as those whose clinical improvement lagged behind their microbiological improvement (ie, they still had symptoms but no bacteraemia).
For management monitoring purposes patients with proven CRBSI were categorized in two subgroups depending on the infection control: a. Controlled, i.e. patients with controlled infection (n = 16), defined as clinical and microbiological improvement and b.
Microbiological improvement was determined as sputum culture negativity for 3 months at 4 6 months after the start of treatment; radiographic regression after 6 months of treatment was determined on the basis of standards described previously 14.
Microbiological improvement occurred in two out of six (33.3%) in group 1, five out of seven (71.4%) in group 2 and one out of two (50%) in group 3. Favorable outcome (discharged to the ward) occurred in one patient out of six (16.6%) in group 1, two out of seven (28.5%) in group 2 and one out of two (50%) in group 3.
At 12 months, both test and control groups were associated with significant but comparable clinical, microbiological and immunological improvements [34, 37] (Table 8).
De-escalation was associated with availability of etiologic microbiological cultures and improvement of the SOFA score.
M. avium lung infection of 30 subjects in whom clarithromycin-containing regimens produced microbiological and radiographic improvement was defined as responsive disease, while that of the remaining 29 subjects was defined as refractory disease.
Significant improvements in microbiological outcome (for example, prevalence of antibiotic-resistant bacteria) and clinical outcomes (for example, mortality and length of hospital stay) were also noted in some studies.
With respect to microbiological raw water quality improvement, MSF units achieved on average 98% Faecal and 96% Total coliform removal.
Bordalo (2003) attributed the dramatic improvement in microbiological water quality to the increase in salinity during high tide in coastal beaches of Portugal.
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