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Results of microbiological documentation were 94 (53) positive microbiological sample and 68 (38) with a positive threshold whose 6 (3) were considered colonized (i.e. no clinico-radiological sign).
Patients with possible IC, that is, the presence of highly suggestive symptoms without microbiological documentation, were not included in the assessment of the performance of the test because of the uncertainty whether they represent true or false positives.
The observations by Phua and colleagues [ 2] tend to confirm earlier epidemiological studies showing that patients with or without microbiological documentation were at similarly high risk of death [ 6- 8].
Similar(57)
Microbiological documentation was achieved in 38.6%.
A microbiological documentation was obtained in 144 (83 %) patients.
Most studies conducted outside of the ICU have enrolled patients in whom microbiological documentation was lacking.
In case of suspected aspiration pneumonia, a microbiological documentation was performed before initiation of probabilist treatment with amoxicillin-clavulanate.
In the 13 remaining cases (12.5 %), a microbiological documentation was obtained in only one sample (BAL: 5, PBA: 8), above threshold in 6 cases (BAL: 3, PBA: 3), below threshold in 7 cases (BAL: 2, PBA: 5).
The microbiological documentation was higher for CBP: 47.37 % vs. 41.66 % (p < 0.001) and in these cases, the treatment was adequate in greater proportion: 28.41 % CBP vs. 38.2 % O-ATB (p < 0.001 ).
Introduction The lack of a patent source of infection and microbiological documentation is not uncommon during the first 24 h management of a septic shock, raising the possibility of non-infectious causes.
Second, more microbiological documentation was available for cases than controls.
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