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This underlines the importance of establishment of relevant microbiological diagnostics and targeted antimicrobial treatment in the management of fever.
10 11 Although locally adapted guidelines may help to enhance microbiological diagnostics and initial antibiotic therapy, these are not always readily available.
A high number of tuberculosis and bacterial infections and a high case fatality rate from sepsis were found in this cohort, underlining the importance of microbiological diagnostics and targeted antimicrobial treatment in the management of fever.
Selected themes include advances in point-of-care diagnostic testing, glucose control, novel microbiological diagnostics and infection control measures, and developments in information technology that have implications for intensive care.
The median IDs of MRSA cases per 1000 patient-days (pd) with the interquartile range (IQR) were calculated from the pooled data of 186 ICUs and correlated with parameters derived from a detailed questionnaire regarding ICU structure, microbiological diagnostics and MRSA screening and control measures.
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Patients with fever of unknown origin not responding to an appropriate first-line therapy after 72 96 h should undergo thorough physical re-examination, imaging (Table 1) and microbiological diagnostics including a native thoracic CT scan and a CT scan of paranasal sinuses if symptoms or signs of sinusitis are present (A-II).
Although ATS criteria represent the cornerstone of NTM diagnosis, some limitations need to be addressed: the uncertain significance of isolation of NTM; the experience and training required in using specific microbiological diagnostic kits; and use of X-ray investigations for NTM identification.
We also omitted questions regarding microbiological diagnostics, infrastructure or tests and policy forming to keep the questionnaire at an acceptable length.
The incidence in Hong Kong was higher than previous estimates from the Asian/Western Pacific region [ 2] highlighting the importance of having adequate clinical and microbiological diagnostics in place.
Point-of-care testing, accelerated microbiological diagnostics, decision support systems and networked IT systems are all key developments that will exert an impact on future critical care practice.
Following this baseline time period, a CDSS for antibiotic therapy was designed as a tool to provide clinicians with essential guideline-based information concerning the treatment of infections, the use of antibiotic agents and microbiological diagnostics in the ICU.
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