Sentence examples for microbicides have demonstrated from inspiring English sources

Clinical trials of PrEP and ARV-based microbicides have demonstrated that although adherence to visits was high in all trials, adherence to product measured objectively through detection of drug varied considerably [ 16– 18, 20, 46].

In this work we have demonstrated an easy and fast in vitro methodology to screen candidate microbicide and spermicide surfactants in the struggle against conception and STD.

Now you have demonstrated.

In this paper, we have demonstrated a multiplexed, Fourier-domain mLCI system that has been adapted to a fluorimetric endoscope system for simultaneous, multimodal optical imaging of microbicide gel coating distribution over the vaginal epithelial surface in women in vivo.

Evidence predominantly from early-phase microbicide trials has demonstrated very high levels of acceptability of gel use among women and men in sub-Saharan Africa (Bentley et al. 2004; Montgomery et al. 2010; Morrow et al. 2003; Ramjee et al. 2007; Vandebosch et al. 2004; Woodsong and Alleman 2008).

Moreover, none of the previous microbicide clinical trials with other candidate drugs has demonstrated significant protection against HIV and in some trials, higher rates of infection were observed in the treatment compared to the placebo arm [3], [4], [5].

And we've demonstrated that".

Having demonstrated HSV-2 infection of macaques and that HSV-2 exposure significantly enhanced the frequency of SHIV-RT infection in this model, we wanted to utilize this system to carry out the first test of a lead microbicide gel comprising the NNRTI MIV-150 in Carraguard (PC-817) for its ability to prevent SHIV-RT infection under these more rigorous conditions.

But three trials of microbicides have now failed, and so have two herpes-suppression trials and one trial of diaphragms.

Several trials of candidate microbicides have had disappointing outcomes [3] [7].

Several phase III clinical trials assessing the effectiveness of microbicides have been conducted over the last decade.