Sentence examples for microbial surface components from inspiring English sources
Kang, M. et al. Collagen-binding microbial surface components recognizing adhesive matrix molecule (MSCRAMM) of Gram-positive bacteria inhibit complement activation via the classical pathway.
Pathogenic bacteria specifically recognize extracellular matrix (ECM) molecules of the host (e.g. collagen, fibrinogen and fibronectin) through their surface proteins known as MSCRAMMs (Microbial Surface Components Recognizing Adhesive Matrix Molecules) and initiate colonization.
The Staphylococcus aureus fibrinogen binding MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules), ClfA (clumping factor A) is an important virulence factor in staphylococcal infections and a component of several vaccines currently under clinical evaluation.
Microbial Surface Components Recognizing Adhesive Matrix Molecules.
This is mediated by S. aureus surface adhesins called Microbial Surface Components Recognizing Adhesive Matrix Molecules (MSCRAMMs) (Gillaspy et al., 1998; Patti et al., 1994).
Bone sialoprotein-binding protein (Bbp), a MSCRAMMs (Microbial Surface Components Recognizing Adhesive Matrix Molecules) family protein expressed on the surface of Staphylococcus aureus (S. aureus), mediates adherence to fibrinogen α (Fg α), a component in the extracellular matrix of the host cell and is important for infection and pathogenesis.
BBK32 is a surface expressed lipoprotein and fibronectin (Fn -binding microbial surFn -bindingent recognizing adhesive microbiallecule (Msurface of Borrelia burgdorferi, the component agent of Lyme disease.
Surface proteins and in particular proteins belonging to "microbial surface component recognizing matrix molecules" (MSCRAMM) were shown to play a functional role in the pathogenesis of all bacteria.
6– 8 The collagen-binding microbial surface component recognizing adhesive matrix molecules on S. aureus is called CNA and is the prototype member of this family.
Many gram-positive pathogens commonly found in diabetic foot ulcers, such as Staphylococcus aureus, Enterococcus faecalis, and Streptococcus equi, are able to bind to collagen by utilizing collagen-binding adhesins of the microbial surface component recognizing adhesive matrix molecules family.
It has been demonstrated that S. gallolyticus subsp. gallolyticus has 11 cell wall-anchored proteins with "microbial surface component recognizing matrix molecules" (MSCRAMM) characteristics, including a collagen-binding adhesin and proteins with similarities to pilus subunits [ 13].
