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The aeration-dependent optimization strategy of TCA cycle will be useful for developing microbial strains producing other reduced derivative chemicals of TCA cycle intermediates.
Focus is given on the strategies of employing synthetic biology and metabolic engineering for the development of microbial strains producing advanced fuels.
The development of efficient microbial strains producing target compounds at high titers, yields, and productivities is required for industrial production.
Industries are often interested in new microbial strains producing different enzymes having original activities.
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This study was designed to evaluate media with the intention of optimizing a drug-discovery screening program, which is a different goal than finding the ideal medium for a specific microbial strain producing one or two key metabolites.
Surely, more research is needed to reveal (i) the dominant processes and (ii) key microbial or fungal strains producing N2O under these specific conditions (especially during early summer period).
Metagenomic approaches, which sidestep the need to purify and cultivate individual microbial strains, make it easier to retrieve genome sequence information from elusive microbial species.
Synthetic biology has reached the point where it is possible to develop microbial strains to produce desired chemicals.
Current efforts focus on the metabolic engineering of microbial strains to produce high levels of desirable end-products.
Biorefinery research is being actively pursued in both developed and developing countries, employing systems metabolic engineering to engineer microbial strains to produce a wide range of value-added biochemicals.
**No. of strains producing biofilm.
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