Sentence examples for microbial specificity from inspiring English sources

The knowledge concerning microbial specificity of ficolin-3 is limited.

Short AMPs are less immunogenic and would therefore be less likely to trigger allergies (Dhiraj et al. 2006), and they would be easier to modify to increase stability, reduce toxicity, or engineer microbial specificity.

In this context, short AMPs (<20 amino acids) lacking disulfide bonds combine optimal antimicrobial activity with inexpensive chemical synthesis and are therefore more compatible with large-scale production and the modifications required to ensure stability, low toxicity, and microbial specificity.

A better knowledge of the genetic basis of microbial host specificity should also lead to the development of recombinant strains of microbials showing narrow specificity (St. Leger and Wang 2010).

Thus, diversification of antimicrobial effectors by accumulation of multiple variations around an originally unique form may provide significant means of acquiring microbial target specificity [ 11], concerned in the evolutionary arms race between pathogens and their hosts.

To study oral microbial enzyme specificities directed at gliadins, we synthesized Z-YPQ-pNA, as well as three other gliadin-derived tripeptide analogs, Z-QQP-pNA, Z-PPF-pNA and Z-PFP-pNA with Z representing benzyloxycarbonyl (protective group) and pNA representing paranitroanilide (reporter group).

Nevertheless, we propose, following several authors [ 24, 25] that strong selective pressures on AMPs are directed toward the acquisition of novel microbial target specificities.

Rhizospheres are known to harbor microbial populations specific to a particular cultivar [30] and this specificity should be incorporated in the allelopathy bioassays [31], [32].

As the main limitation of this and other similar microbial assays non-specificity is usually assumed (Bilandzic et al. 2011).

mTet1 efficiently converted 5mC to 5caC in synthetic oligonucleotides, in vitro methylated plasmids, bacterial genomic DNA and mammalian genomic DNA [ 14], facilitating identification of microbial 5mC MTase specificities, thus complementing the other two common, readily detectable bacterial methylation marks of m6A and m4C described previously [ 16, 17].

Specifically, we highlight emerging in situ genome engineering approaches as tractable techniques to manipulate microbial communities with high specificity and efficacy.