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Alternative agents specifically designed to overcome mechanisms of microbial resistance have been sought.
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The increasing prevalence of microbial resistance has made the management of public health an important issue in the modern world.
Antimicrobial properties vary according to the environment where honey is collected and microbial resistance has never been reported.
Antibiotics represent an emerging environmental problem due to their disposal into the aquatic ecosystem, even at minimum inhibitory concentrations (MICs) and increasing of microbial resistance that has occurred as one of the eminent public health concerns of the twenty-first century (Klavarioti et al. 2009: Velickovic-Radovanovic et al. 2009).
Although similar reduction of microbial resistance after disuse had been reported in other parts of the world [ 16], a number of studies have reported contradictory results [ 13].
Although relatively rare at present, microbial resistance to carbapenems has reached clinically important levels for several organisms, including Pseudomonas aeruginosa, Acinetobacter spp., Klebsiella spp., and Escherichia coli.
The clinical importance of microbial causes of dacryocystitis and pattern of drug resistance has not been reported in northwest Ethiopia.
Antimicrobial resistance has been noticed as one of the paramount microbial threats of the twenty-first century [ 21].
Resistance has, nevertheless, emerged.
But resistance has weakened.
Diplomatic resistance has no effect.
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