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Microbial proteases are one of the largest groups of industrial enzymes.
Microbial proteases are also used widely as biocatalysts in organic synthesis.
Microbial proteases are one of the most commercially valuable enzymes, of which the largest market share has been taken by subtilases or alkaline proteases of the Bacillus species.
Microbial proteases are one of the most commercially valuable enzymes [ 1], of which the largest market share has been taken by subtilases or alkaline proteases of the Bacillus species, which has been extensively studied in terms of both biological properties and applications [ 1- 3].
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Different crude microbial proteases were applied for chitin extraction from shrimp shells.
The industrial production of microbial proteases is favored due to the fact that they have a short generation time, because of the ease of genetically manipulating microorganisms, and because of the diversity of species available in nature, many of which are still unexplored [ 2, 3].
Regarding the suitability of the enzymes in the protein hydrolyzation field, Alcalase, a microbial protease, is most preferred and is widely used.
However, various animals, plants, and microbial proteases have been suggested as milk coagulants (Zhang et al. 2011), but still attention has been focused on production of milk-clotting enzymes from microbial sources (Silveira et al. 2005; Wu et al. 2013) due to their rapid growth, relative inexpensive growth substrate, and diverse properties.
Generally, microbial proteases have been produced by fermentation under controlled conditions.
Haemolymph clotting and production of anti-microbial peptides and proteases are the typical insect humoral responses against pathogens.
Similarly, the property of microbial serine proteases was reported for polyethylene succinate biodegradation (Lim et al. 2005).
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