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The increasing resistance of microbial pathogens to either antibiotics or antifungal drugs is a major health problem and is of global interest.
The current accessible drug regimen on prolonged treatment was making these microbial pathogens to become resistant and causing urge in need of newer anti microbial agents with superior mode of action [1, 2].
The potential of drinking water to transmit microbial pathogens to great number of people causing subsequent illness is well documented in many countries at all levels of economic development (Dufour et al. 2003).
The intestinal epithelium as a critical component of a communications network that is essential for transmitting signals generated in response to infection with microbial pathogens to cells of the innate and acquired immune systems in the underlying intestinal mucosa.
The hemolysis mainly caused by hemolysins is thought to be a virulence activity of numerous microbial pathogens to degrade tissues, invade host cells, disseminate themselves, and escape from the host immune attack.
These results suggest a strategy commonly used by microbial pathogens to manipulate the host cellular function through histone modification and subversion of host innate immune responses for their survival or infection advantage.
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By contrast, there was up-regulation in a number of virulence genes in response to exposure of the microbial pathogen to host epithelia.
A supply of micronutrients like zinc is essential for a microbial pathogen to survive and disseminate during an infection.
Cavity-nesting and ground-nesting species may experience greater exposure to fungal and other microbial pathogens due to the increased proximity to damp soil and rotting wood, which could in turn favor multiple paternity.
Microarrays have recently been employed successfully to identify the molecular pathways involved in the pig response to a number of different microbial pathogens and to identify disease resistance candidate genes [ 15- 18].
The co-evolutionary arms race between the plant host and microbial pathogens leads to reciprocal selective pressure for the interacting proteins to change.
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