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Receptor-mediated glycan-binding events underlie selective adhesion between mammalian cells, sorting and trafficking of soluble glycoproteins, and detection of microbial pathogens based on their surface glycosylation (Taylor and Drickamer 2006; Varki et al. 2009).
Although dose response relations have been published for several microbial pathogens based upon human challenge studies, such information is normally not available for pathogens that can cause severe illness, such as C. burnetii.
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In contrast, biological soil disinfestation (BSD), mainly developed in the Netherlands (Blok et al. 2000) and Japan (Shinmura 2004) in organic agriculture, suppresses soil pathogens based on microbial activity on incorporated plant biomass under anaerobic conditions without using any chemical fumigants.
In vitro research suggests plant LTPs function in plant defense against pathogens based on their ability to inhibit microbial growth.
In this review we will only focus on the few examples that describe a direct involvement of microbial pathogens in EMT induction based on their ability to modulate E-cadherin expression via an increase of the core EMT regulatory factors.
This new approach based on text and data mining can support the discovery of previously hidden associations between diseases and microbial pathogens, clinically relevant reclassification of pathogenic microorganisms and accelerate the translational research enterprise.
A preliminary subtractive screening based on the abilities to inhibit the growth of microbial pathogens and hydrolyse conjugated bile salts was applied to the strains.
Recently, many studies have demonstrated the significant advantages of loop-mediated isothermal amplification (LAMP) based methods over serological tests and PCR for rapid detection of microbial pathogens.
Different microbial pathogens use diverse sets of virulence factors to establish infections.
Alternatively, chlorine based commercial vegetable and fruit sanitizers, are considered to be very effective to reduce/kill microbial pathogens.
Increasingly, DNA based assays that detect known genomic signatures have been developed that offer rapid and reliable identification of microbial pathogens [3], [4].
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