Moreover, analysis of our model cells revealed that LPS priming enforces the production of anti-microbial factors, protects integrity of the epithelial cells through enforced tissue stabilization and wound healing.
This suggests that the integrity of microbial cell factories could be checked during fermentation by determination of the fluorescence in culture supernatant.
In order to assess the integrity of the microbial cells, biofilms were developed in a Lab-Tek TM coverslip chambers (Nunc) as described above, and treated with standard drugs and EOs at 1 mg/mL.
Recent evidence supports the role of microbial factors in maintaining the structural integrity of epithelial tissues.
As a result, the humid, ventilated caverns could provide many potential niches for microbial growth, which could influence both the integrity of the storage casks (and any associated infrastructure) and the subsequent long-term performance of the sealed repository.
The role of microbial factors in the regulation of structural integrity of mucosal tissues has been investigated in several recent studies.
Microbial invasion originates from a breach of integrity of the host barrier, either physical or immunologic.
A key distinction of natural SIV infections is rapid and active control of immune activation and apoptosis of T cells that contributes to the integrity of mucosal barrier and lack of microbial translocation.
Microbial recognition is a complex process that depends on the integrity of the complement system and requires specialized receptors on natural killer cells and nucleotide-binding oligomerization domain (NOD) proteins [ 1].
Furthermore, chronic SIV infection in natural hosts does not undermine the integrity of mucosal barrier, and consequently, there is no increase in microbial translocation [ 30, 31].
