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Their efficacy in prevention and treatment of various microbial infections has been evaluated in numerous studies.
Autoreactivity to heart antigens caused by microbial infections has been described in several heart diseases [ 2, 9, 10, 35, 36, 45- 47].
Research into the pathogenesis of microbial infections has a long and fruitful history, rich with elucidation of mechanisms that have resulted in better treatments and new strategies for vaccine development.
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The intensely increasing multi-drug resistant microbial infections have encouraged the search for new antimicrobial agents.
Previous studies conducted in various parasitic and microbial infections have shown CD23 expression together with its role in intracellular and extracellular killing of pathogens by macrophages [3], [8], [10].
Plants used for the treatment of microbial infections have also been heavily explored.
Microbial infections have become one of the principal problems of public health in the world, affecting all countries, developing or developed.
In addition, phytoalexins, which are hydroxylated derivatives of coumarins, which are produced in plants in response to microbial infections, have been found to exert marked antifungal activity.
The importance of these associations in microbial infection has been reported.
Detailed examination of a single bacterial effector molecule in the context of microbial infection has so far proven difficult, since type III secretion systems can deliver multiple effector proteins at any given time (Galán and Collmer, 1999).
Many factors such as inflammatory and immune responses as well as microbial infection have been reported to impair and delay the healing process.
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