Sentence examples for microbial genome sequencing from inspiring English sources
While traditional microbiology and microbial genome sequencing and genomics rely upon cultivated clonal cultures, early environmental gene sequencing cloned specific genes (often the 16S rRNA gene) to produce a profile of diversity in a natural sample.
The genome sequencing of R. litoralis was carried out at the J. Craig Venter Institute (Rockville, MD, USA) within the Microbial Genome Sequencing Project by a Sanger sequencing-based approach.
The NSF Biological Sciences Directorate funded genomics research under the following three programs: Microbial Genome Sequencing Program, the Plant Genome Project, and the 2010 Project (Personal Communication, Vernon Ross, April 2007).
All three of these lesser studied types of infection would result in the assembly of viral sequences outside of the main host chromosome in a microbial genome sequencing project and could be a new type of viral signal in modern microbial genomic data sets due to deep sequencing and public release of draft (i.e., not completely assembled) genomic sequences.
The recent surge in microbial genome sequencing has produced a wealth of genetic data available for comparative genomic analyses to make possible the identification of diverse essential enzymes in critical metabolic pathways within the Archaea and Bacteria.
Microbial genome sequencing has the potential to substantially increase the speed of antibiotic resistance detection for many pathogens2 and in addition provides valuable information on relatedness that could contribute to surveillance.
Expanding databases of complete microbial genome sequences facilitate a comparative genomic approach that can provide valuable insight into the role of uncharacterized proteins.
The availability of a complete microbial genome sequence in 1995 marked the beginning of a genomic era that has allowed scientists to change the paradigm and approach vaccine development starting from genomic information, a process named reverse vaccinology.
With the advent of next-generation DNA sequencing technologies, the number of microbial genome sequences has increased dramatically, revealing a vast array of new biosynthetic gene clusters.
The explosion of microbial genome sequences has shown that bacteria harbor an immense, largely untapped potential for the biosynthesis of diverse natural products, which have traditionally served as an important source of pharmaceutical compounds.
Comparative analysis of the growing number of microbial genome sequences has shown a high plasticity of genomes and several mechanisms for the adaptation of microbial cells to changing environmental conditions have been discovered.
