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The primary nucleotide accession numbers of the genes of bacterial/archaeal origin heterologously expressed in S. cerevisiae were obtained from GenBank or the Integrative Microbial Genome database (IMG) and are listed in Table 3.
The original host was searched using Blastn and the microbial genome database on the NCBI.
Of the 53 sequenced α-proteobacterial genomes currently available on the NCBI microbial genome database (http://www.ncbi.nlm.nih.gov/genomes/lproks.cgi), 16 are known to contain plasmids.
Homology searches in the Listeria genome databases Listilist (for L. monocytogenes and L. innocua) and LivaList (genolist.pasteur.fr/LivaList) for L. ivanovii and in the NCBI microbial genome database (http://www.ncbi.nlm.nih.gov/sutils/genom_table.cgi) yielded the following results.
In this report, we analyzed all annotated protein sequences that are ≤100 amino acids (AA) from 532 completed genome data, including 491 sequences of Bacteria and 41 sequences of Archaea, deposited in the Microbial Genome Database at the National Center for Biotechnology Information (NCBI) [10].
We analyzed 14 haloarchaeal genomes that were available in the NCBI completed microbial genome database.
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Genome annotation was conducted using multiple reference genomes, including 'Ca. L. asiaticus' (GenBank accession # CP001677) and other related microbial genome databases obtained from GenBank.
This study is the first attempt to integrate online repositories of text-based publications and microbial genome databases in order to explore the dynamics of relationships between pathogens and infectious diseases.
MCT analyzed microbial genome databases.
Many types of microbial genome databases exist.
The GenoList package for collecting and mining microbial genome databases has been rewritten using MySQL as the database management system.
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