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This suggests an inhibitory effect of a cellular or microbial factor present in the co-culture medium.
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Here, we showed that serum levels of LPS were higher in mice fed lard compared to mice fed fish oil, indicating that microbial factors are present in the periphery that may directly affect WAT inflammation.
Recently, it has been demonstrated that inhibition of microbial secreted virulence factors present less selective pressure for the generation of resistance [58].
Multiple microbial factors promote development of TH2-inflammation, including the influence of certain microbial adjuvants during antigen presenting cell activation, and the nature of the protein itself.
Whether a microbe is helpful or harmful is highly dependent on complex host and microbial factors.
Interestingly, some recent studies also revealed that microbial factors interfere with epithelial EGFR signaling.
Recent evidence supports the role of microbial factors in maintaining the structural integrity of epithelial tissues.
Both host and microbial factors contribute to its pathogenesis.
Both host and microbial factors play a role in pathogenesis.
All these factors have confounded the assessment of microbial factors associated with gingivitis.
It should be noted, however, that many other factors present in soil would accelerate protein degradation, such as microbial activity.
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