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This frontier of microbial discoveries has largely been unexplored due to a number of challenges, which are due to the lower density of microorganisms in the air; inefficient retrieval of microbes and their nucleic acids from the air; lack of standardized approaches and methodologies; and bioinformatics-related challenges of de novo genome reconstruction.
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Nathan Cude works in Novozymes' agbiotech division in Durham, North Carolina in the microbial discovery group, which isolates and identifies thousands of microbes collected from soil samples around the United States.
The advent of molecular-based methods of identification and characterization of complex microbial populations has led to a new era of microbial discovery.
We therefore identify cold environments as promising targets for microbial discovery.
Polar environments therefore hold a high potential for future research on microbial discovery.
Non-human RNA sequences were subjected to a microbial discovery bioinformatics platform, and microbial sequences were analyzed by Metastats for association with KD.
Several groups have designed microarrays containing probes for microbial detection, discovery, or a combination of both [ 3- 8, 10- 20].
This special issue includes five papers (three reviews and two research papers) addressing diverse aspects related to the understanding and eventually facing the current bottlenecks in the process of microbial product discovery and development.
Therefore, the potential of microbial genomics for discovery of new drugs should not be underestimated.
Molecular approaches for microbial surveillance and discovery have emerged as a very promising alternative for early diagnosis of infectious diseases.
Most currently available methods for microbial detection and discovery using nucleic acid samples are based on three technologies.
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