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Co-culture engineering is an emerging approach for microbial biosynthesis of a variety of biochemicals.
Engineered microbial biosynthesis of plant natural products can support manufacturing of complex bioactive molecules and enable discovery of non-naturally occurring derivatives.
Microbial biosynthesis of FFAs can be achieved by introducing an acyl acyl carrier protein thioesterase into Escherichia coli.
Microbial biosynthesis of fatty acid like chemicals from renewable carbon sources has attracted significant attention in recent years.
Microbial biosynthesis of fatty acid-derived biofuels from renewable carbon sources has attracted significant attention in recent years.
Engineered microbial biosynthesis of medium chain length alkanes, which constitute the major fraction of petroleum-based jet fuels, was recently demonstrated.
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Microbial biosynthesis for plant-based natural products, such as the benzylisoquinoline alkaloids (BIAs), has the potential to address limitations in plant-based supply of established drugs and make new molecules available for drug discovery.
Yet, increasing requirements for sophisticated microbial biosynthesis call for establishment and application of more advanced metabolic engineering methodologies.
At present, chemical hydrotreatment of acylglycerides, fatty acids, or fatty acyl esters, and de novo microbial biosynthesis are the two major strategies for production of biohydrocarbons.
Microbial biosynthesis has provided an interesting way to the sustainable production of biofuels.
Recent advances in metabolic engineering have demonstrated that microbial biosynthesis can provide a viable alternative to chemical synthesis for the production of bulk and fine chemicals.
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