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The fright and flight experience of panic that characterized yellow fever and cholera outbreaks began to change around the turn of the century as scientists identified the microbes that caused disease.
Dr Lee's group, which has since grown to a dozen, slowly developed ways of simplifying complex medical tests that could then be tailored to pick up different infections by tuning them to detect specific proteins, strands of genetic material and other molecules unique to the viruses and microbes that caused the diseases in their sights.
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This is because the microbes that cause them are constantly evolving.
As promising as these techniques were, they also made it possible for scientists to transfer viruses — and microbes that cause cancer — from one organism to another.
"Essentially, the microbes that cause rotting are a lot like ourselves, in that they need water, nutrients, warmth and time to grow.
Under U.S. guidelines, BSL-3 facilities contain microbes that cause "serious or potentially lethal diseases" but do not easily pass among people, or for which there are easily accessible preventives.
Such diseases must affect humans, not animals; produce no asymptomatic carriers who could silently spread the microbes that cause them; and be preventable by a vaccine or curable by a drug.
Among the 49 exhibits was Gilbert Schmidling's Ulexite, an opaque fibrous rock which can transfer an image from one end of itself to the other, John Lee's colony of trypanosome - lethal microbes that cause sleeping sickness, and James V. Lawrence's cross section of some hairs of buckthorn, which was unfortunately duplicated by another member.
Gram-negative bacteria comprise the majority of microbes that cause infections that are resistant to pre-existing antibiotics.
The bacteria includes the familiar microbes that cause disease and help make yogurt, whereas the archaea includes microbes that live in extreme environments, like boiling hot water emerging from volcanic vents at the bottom of the ocean.
Now, a genetic study of the microbes that cause food poisoning suggests that the evolution of bacterial species might not be so different from that of finches after all.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com