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Environmental microbes are in a continuous antibiotic arms race that is likely to select for antibiotic variants capable of circumventing existing resistance mechanisms.
Even at this time, which some hypothetical historian of the future could call the Age of the Macrobes, microbes are in fact the main actors in the world.
"The DSRS is an amazing and powerful new tool, the first example of a synthetic system that can dynamically regulate a metabolic pathway for improving production of fatty acid-based fuels and chemicals while the microbes are in the bioreactor," says Jay Keasling, CEO of JBEI and one of the world's foremost practitioners of synthetic biology, who led this research.
What chemicals or microbes are in it?
Unfortunately, appropriate temperatures for the enzymes and microbes are in general very different.
Then there's the lingering question of how effective chemical dispersants or oil-munching microbes are in the frigid Arctic environment.
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But this apparently superficial relationship between food and microbes is in reality rather profound because first it speaks of a co-evolution with the human body over tens of thousands of years.
Moreover, the pH required for an optimal growth and metabolism of the common microbes were in the range of 5.0 8.0.
In some experiments, the researchers put the microbes in a 300-milliliter container with constant water circulation; in other experiments, the microbes were in a 4-milliliter-long chamber with a glass cover.
It is found that a natural perspective for understanding a microbe is in terms of a hierarchy of variables at various levels of resolution.
"With many diseases we encounter, the microbe is in our body to begin with, but when the environment changes it becomes an opportunist".
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