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> -wrap-foot> Analysis of melanoma cell lines by gene expression microarrays has identified a large cohort of hypermethylated genes.
The introduction of cDNA microarrays has identified changes in the expression of hundreds of genes in post-mortem brain tissue from individuals with schizophrenia [ 1- 14].
Analysis of the transcriptional profile of C. albicans using RNA-seq and microarrays has identified several hundred, and possibly several thousand novel transcribed regions (nTARs) that are unlikely to encode proteins [ 29- 31].
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Studies on the transcriptional changes in C. elegans that accompany infection by different pathogens, often using microarrays, have identified many genes involved in the response to infection [7], [8], [9], [10], [11], [12], [13].
Gene expression studies using DNA microarrays have identified several distinct breast cancer subtypes which differ significantly in prognosis [ 1, 2].
Meanwhile, several recent studies using cDNA microarrays have identified some nuclear target genes downstream of the pathway of CMS occurrence [ 27, 28].
DNA microarrays have identified calbindin, desmoplakin, tryptophan-2,3-dioxygenase and interleukin-1 receptor type 1 as dentate gyrus enriched genes (Lein et al., 2004; Hagihara et al., 2009).
Studies with subtractive hybridization and microarrays have identified 16 regions present in M. tuberculosis H37Rv but are absent in M. bovis BCG [ 1, 8].
Various gene expression analysis approaches, including microarrays, have identified aberrantly expressed miRNAs in OC [ 9, 11- 26], of which some are related to progression [ 13], outcome [ 18- 24] and chemotherapy resistance [ 23- 25].
In mouse ESCs (mESCs) undergoing embryoid body formation, exon-spanning microarrays have identified possible alternative splicing events in genes associated with pluripotency, lineage specification and cell-cycle regulation [ 22].
Necrotic inducing proteins expressed by M. perniciosa have been characterized [ 19], and the analysis of EST libraries and DNA microarrays have identified differentially expressed genes during its development [[ 20]; A.B.L. Pires et al., unpublished data] and for the interaction of the fungus with cacao [ 21, 22].
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