Vegas, A.J. et al. Fluorous-based small-molecule microarrays for the discovery of histone deacetylase inhibitors.
We thank S. Geffroy for technical support and running the microarrays for the ALFA-0701 trial cohort.
Berger, M. F. & Bulyk, M. L. Universal protein-binding microarrays for the comprehensive characterization of the DNA-binding specificities of transcription factors.
The chapter focuses on the application of microarrays for the analysis of Mycobacterium tuberculosis inside host cells.
David's current research employs optical fiber microarrays for the detection and analysis of single enzyme molecules to provide mechanistic insight into enzyme mechanisms.
Here, we describe the construction and validation of microarrays for the fungus Aspergillus nidulans using PCR products from a 4092 EST conidial germination library.
Thus, these modifications result in a specific, sensitive, and rapid microarray assay and may be used for constructing microarrays for the detection of all influenza subtypes and strains.
Next, microarrays for the RNAs from mouse medullary collecting duct cell line (mIMCD) cells and osmotically adapted mIMCD cells (HT cells) were performed (designed as resistant to 1270 mOsm/H2O).
These results illustrate a significant step forward in the development of the DNA chip technology for nematode detection, and constitute to our knowledge the first report of production and use of oligonucleotide microarrays for the detection of plant-parasitic nematodes, using the quarantine species M. chitwoodi as a test organism.
Combined with large cellular microarrays for the assay of cellular gene expression, global descriptions of transcript abundance in specific cells and tissues provides an important component of a total molecular description of the course of viral infection and pathogenesis, which are readily applied to the development of strategies for the treatment and palliation of virus-induced morbidity.
In 2001 Dr. Dressman became the Director of the Microarray Core Facility and established the facility to provide the infrastructure to enable the development of major projects that utilize DNA microarrays for the large scale analysis of gene expression and services to investigators at Duke.
