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Since the rhesus macaque genome has only recently been sequenced [9], the rhesus microarrays are based primarily on gene predictions.
Base addresses for the microarrays are based on the NCBI Build 36/mm8 (February 2006) assembly of the Mus musculus genome.
However, the production of a good reference becomes unfeasible when microarrays are based on pan-genomes.
Nearly all the fully tested and characterised protein microarrays are based on antibody technologies.
Many of the analysis techniques that are aimed at identifying the functional role of elements in biological systems, such as gene expression microarrays, are based on studying correlations in the data.
Although providing insight, microarrays are based on a priori knowledge and oligonucleotide design and may not detect lowly expressed transcripts or provide complete genome coverage due to lack of probe availability.
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The design of these microarrays is based on LIPOchip, version 4, which detects 191 LDLR and APOB mutations identified in Spanish patients with FH.
The first widely used microarrays were based on cDNA sequences [1].
The main operational principal of microarrays is based on specific binding of DNA or RNA target to oligonucleotide probes synthesized on the array surface.
The microarrays were based on a testis and brain library from the same populations of RJF and WL as used in the present experiment [16].
* Although [ 25] studied the effects in strain D39, the used microarrays were based on strains TIGR4 and R6.
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