If a statistically significant enrichment of expressed FBX genes was observed in a microarray dataset, the biological functions tested by the microarray was retrieved.
Unigene sequences of the tomato and the potato microarrays were retrieved from the manufacturers (CGEP and TIGR, respectively).
Human gene sets obtained from published experiments using microarrays were retrieved in order to identify gene networks 1/regulated by glucose in healthy liver 2/dysregulated in HCC 3/differentially affected in HepG2 and HuH7 cell lines (Table 1).
In addition, RMA-normalized data from 871 microarrays were retrieved and the Affymetrix probe sets corresponding to OSK genes enabled the identification of 20 non-ambiguous Probe set OSK pairs.
A set of dendritic cell samples unstimulated or stimulated with poly(I C) and hybridized on Affymetrix microarrays was retrieved from Array Express (accession code E-MEXP-1230 E-MEXP-1230 E-MEXP-1230
The target gene regions of microarray probes were retrieved from the annotation file for human U133 Plus 2.0 (http://www.affymetrix.com).
Additional porcine genome sequence representations for uncharacterized microarray genes were retrieved from Emsembl Trace Server [35].
Published microarray data were retrieved from Gene Expression Omnibus (GEO) [ 49].
A total of 1092 microarray datasets were retrieved.
The microarray data were retrieved from the Tetrahymena Gene Expression Database (TGED, http://tged.ihb.ac.cn/).ihb.ac.cn/
