The first large-scale gene expression profiling study (skin cDNA microarrays) was undertaken using resistant/susceptible Adaptaur cattle and identified several candidate mechanisms (e.g. antibody immune response day 1 of the infestation) that were involved in Adaptaur tick resistance (Wang et al. 2007).
Transcriptomic analyses using Agilent D. magna oligonucleotide microarrays were undertaken to assess the effect of a mixture of sodium dichromate and BaP (designed to produce both adducted and oxidised DNA) on gene transcription.
RNA amplification was performed using Ambion Total Prep kit (Ambion, UK) and microarrays were undertaken using Illumina chips according to the manufacturer's protocol.
To better define this condition, an investigation using histopathology, confocal microscopy, biochemistry and microarray analysis was undertaken.
A microarray study was undertaken to define the gene expression profile in response to exosome treatment on a global scale.
To gain more insight into how the fork speed is changed, for instance to see if there are pauses at certain chromosomal sites, a microarray experiment was undertaken.
MiRNA microarray analysis was undertaken to examine the spectrum of cellular miRNAs in primary human astrocyte and human U-87 astrocytoma cells and then compared to those associated with the RISC of the respective cells.
This investigation, for which all the work, with the exception of the microarray data, was undertaken in Ho Chi Minh City, highlights the benefits of having rapidly available multidisciplinary expertise at the site, capable of conducting detailed clinical, epidemiological, and molecular analysis of the outbreak and the causative microorganism.
Hybridisation, washing and scanning of the S. aureus microarray (SAv1.1.0) was undertaken as described previously [ 93].
Statistical analysis of the microarray data was undertaken using background corrected mean signal intensities from each dye channel.
